Quick Facts
FONT-SIZE Plus   Neg
Share SHARE

Genzyme's Gaucher Drug Shows Positive Results In Follow Up Data Of Phase 2 Trial

RELATED NEWS
Trade SNY now with 

Genzyme Corp., a unit of Sanofi-Aventis (SNY: Quote,SNYNF.PK), Wednesday said that a four-year follow-up data from a phase 2 trial for its investigational oral drug 'eliglustat tartrate' for Gaucher disease, showed further improvements across all endpoints.

Sustained or further improvements were observed across all endpoints, including markers of bone disease, at the four-year timepoint, Genzyme said in a statement.

Gaucher disease (pronounced Go-shay) is an inherited genetic disorder, in which patients lack the normal form of glucocerebrosidase, or GCD enzyme that breaks down specific fat molecules. The lack of this enzyme results in the accumulation of fat in liver, spleen and bone marrow. The disease affects about 1 in 100,000 persons in the general population.

Genzyme previously reported that the 52-week phase 2 trial of eliglustat tartrate had met its primary composite endpoint. Patients have continued to receive eliglustat tartrate in the extension portion of the study for over four years. The data from patients on eliglustat tartrate after four years indicate continued or stabilized improvements across all endpoints.

The composite endpoint is clinically meaningful response in at least two of three endpoints i.e. improvements in spleen size, hemoglobin and platelet levels in individual patients.

Register
To receive FREE breaking news email alerts for Sanofi and others in your portfolio

by RTT Staff Writer

For comments and feedback: editorial@rttnews.com

Business News

Quick Facts

Editors Pick
After reporting a sharp increase in existing home sales in the previous month, the National Association of Realtors released a report on Tuesday showing that existing home sales once again rose by more than expected in the month of June. With traders reacting positively to the latest earnings and economic news, stocks have moved mostly higher in early trading on Tuesday. The major averages have all climbed into positive territory, offsetting the modest weakness seen in the previous session. With energy prices showing a significant increase amid rising gasoline prices, the Labor Department released a report on Tuesday showing that U.S. consumer prices rose in line with economist estimates in the month of June.
comments powered by Disqus
FREE Newsletters, Analysis & Alerts

 

Stay informed with our FREE daily Newsletters and real-time breaking News Alerts. Sign up to receive the latest information on business news, health, technology, biotech, market analysis, currency trading and more.