logo
Share SHARE
FONT-SIZE Plus   Neg

AVI BioPharma Gets FDA Approval To Proceed With AVI-7288 To Treat Marburg Virus

AVI BioPharma, Inc. (AVII) Tuesday announced that the U.S Food and Drug Administration, or the FDA, has granted approval to the company to proceed with a single oligomer, AVI-7288, in studies in both humans and non-human primates to support the safety and efficacy of post-exposure prophylaxis against Marburg virus infection.

The company stated that AVI-7288 is one of two components that make up AVI-6003.

The company further added that it will proceed with dosing AVI-7288 in the Phase I multiple ascending dose studies planned to characterize the safety, tolerability and pharmacokinetics of multiple doses of the drug in healthy adult volunteers.

"While we have not seen any toxicity in humans to date with AVI-6003, by removing AVI-7287 we have a simpler development path and may improve the therapeutic window by evaluating a single action agent," said Chris Garabedian, president and CEO of AVI BioPharma. "We are pleased to be able to explore this single oligomer as a potentially safe and effective treatment against this lethal hemorrhagic fever virus."

by RTT Staff Writer

For comments and feedback: editorial@rttnews.com

Business News

Quick Facts

Editors Pick
Volkswagen AG's all electric Microbus might be available in market by 2022. As per the plan it would be available first in California. Microsoft Corp. has unveiled a new Minecraft limited edition version of the Xbox One S console during its Gamescom press conference in Germany. The pixelated device comes with 1TB of storage. It includes a custom designed grass block console, Xbox Wireless Controller - Minecraft Creeper, Minecraft system sounds, vertical stand and transparent underside with Redstone circuit accents. HTC Corp. has cut the price of its Vive virtual reality headset by $200, bringing down the system's cost to $599. The company noted that the new entry price will make the system more accessible to the mass market across the globe. The price cut for the Vive VR headset comes after the Oculus Rift's $200 price cut recently.
comments powered by Disqus
Follow RTT