Breaking News
FONT-SIZE Plus   Neg
Share SHARE

Bayer Says International Study Affirms Xarelto's Benefits In Venous Blood Clots

Bayer HealthCare, a subsidiary of the German conglomerate Bayer AG (BAYRY.PK,BAYZF.PK), Tuesday said an international study that examined the safety and efficacy of Xarelto (rivaroxaban) in preventing potentially deadly venous blood clots reaffirmed the benefits of the drug.

The study, which Bayer calls real-world XAMOS study, assessed rivaroxaban in preventing venous blood clots (venous thromboembolism) in adults, following elective total hip or knee replacement surgery. The study reaffirmed the benefits of the oral, once-daily anticoagulant in everyday clinical practice.

Bayer also said XAMOS supports the clinical findings of and earlier trial programme, which showed oral, once-daily rivaroxaban to have consistently superior efficacy as well as a comparable and good safety profile to injectable enoxaparin.

Rivaroxaban, marketed under the brand name Xarelto, was discovered in Bayer HealthCare's Wuppertal laboratories in Germany, and is being jointly developed by Bayer HealthCare and Janssen Research & Development, LLC.

A.G.G. Turpie, Professor of Medicine, McMaster University, Canada and Chairman of the XAMOS Executive Steering Committee stated, "As the largest analysis of everyday clinical experience with a new oral anticoagulant, XAMOS offers real-world evidence and confidence that oral, once-daily rivaroxaban is safe and effective in protecting against dangerous blood clots in the orthopaedic setting - and importantly without the inconvenience and discomfort of current standard injectable treatments."

The non-interventional XAMOS study compared outcomes observed in everyday clinical practice across 17,413 orthopaedic patients receiving rivaroxaban or conventional pharmacological treatments for blood clot prevention.

The incidence of symptomatic thromboembolic events was lower in patients treated with rivaroxaban compared with conventional therapy.

In the U.S., rivaroxaban is available since July 2011 and Janssen Pharmaceuticals, Inc., a Johnson & Johnson unit, holds marketing rights.

Last week, Bayer HealthCare said it has submitted an application to the European Medicines Agency seeking marketing authorization for Xarelto. In mid-January, Bayer announced that Xarelto has been approved by the Japanese Ministry of Health, Labor and Welfare.

On Frankfurt's Xetra, Bayer shares are currently trading at 51.84 euros, up 1.77 percent, on a volume of 764 thousand shares.

Register
To receive FREE breaking news email alerts for Bayer AG and others in your portfolio

by RTT Staff Writer

For comments and feedback: editorial@rttnews.com

Business News

Editors Pick
Stocks moved notably higher over the course of the trading day on Friday after initially showing a lack of direction. The gains on the day extended the recent upward trend by the markets, with the tech-heavy Nasdaq reaching its best closing level in almost a month. Looking to capitalize on news of an Ebola diagnosis in New York City, Republican Senate candidate Scott Brown issued a statement Friday criticizing his Democratic opponent Sen. Jeanne Shaheen, D-N.H., for "waffling" on a travel ban. In another troubling sign for Democrats, the results of a Gallup poll released on Friday show that Tea Party Republicans are much more motivated to vote in the upcoming midterm elections than other Americans. The poll found that 73 percent of Tea Party Republicans are "extremely" or "very" motivated to vote in this year's elections.
comments powered by Disqus
FREE Newsletters, Analysis & Alerts

 

Stay informed with our FREE daily Newsletters and real-time breaking News Alerts. Sign up to receive the latest information on business news, health, technology, biotech, market analysis, currency trading and more.