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Sanofi, MJFF Collaborate On Potential New Treatment For Parkinson's Disease

Sanofi (SNY,SNYNF.PK) said it has entered into a collaboration with the Michael J. Fox Foundation, or MJFF, to conduct a clinical trial to assess the safety and tolerability of AVE 8112, a Sanofi PDE4 inhibitor - phosphodiesterase type 4 inhibitor - in patients with Parkinson's disease.

As per the terms of the collaboration, MJFF will sponsor a phase I b clinical trial to assess the safety and tolerability of AVE8112 in patients with Parkinson's disease. All data and results generated by the clinical trial will be owned by MJFF and shared with Sanofi. The company noted that further development plans will be based upon the results of the study.

Todd Sherer, chief executive officer of MJFF, stated, "AVE8112 has shown promising pro-cognitive activity in preclinical models that could be of interest to the under-addressed cognitive aspects of Parkinson's disease, an area of unmet need where a new treatment could make a tangible difference in patients' lives. Groundbreaking collaborations with like-minded partners such as Sanofi are a hallmark of the Fox Foundation's approach and help us speed scientific advances with potential to improve the treatment of Parkinson's for patients today and in the future."

Patient enrollment in the study is expected to begin later 2012.

by RTT Staff Writer

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