logo
Share SHARE
FONT-SIZE Plus   Neg

Merck KGaA Says PETACC-8 Study Of Erbitux Shows No Benefit At Interim Analysis

Merck KGaA (MKGAY.PK) revealed results from an interim analysis of the Phase III clinical trial PETACC-81.

The study investigated the potential clinical utility of Erbitux (cetuximab) for the adjuvant treatment of stage III colon cancer after complete surgical removal of the primary tumor.

The pre-specified interim analysis of the study did not support benefit in disease free survival for patients given Erbitux plus standard chemotherapy (FOLFOX 4) compared with patients treated with FOLFOX 4 alone. Therefore this interim analysis does not support the use of Erbitux for the adjuvant treatment of stage III colon cancer in this setting.

"We are disappointed not to see an improvement in disease free survival after 3.3 years of median follow up" said Professor Julien Taïeb from the Hôpital Européen Georges Pompidou, Paris, and the PETACC-8 Principal Investigator. "Unfortunately, since the introduction of FOLFOX as standard treatment, all attempts to further improve prevention of disease recurrence have proved unsuccessful. We look forward to sharing our data at future scientific congresses."

by RTT Staff Writer

For comments and feedback: editorial@rttnews.com

Business News

Quick Facts

Editors Pick
GoPro Inc. (GPRO) has launched two new mobile video editing applications for its users. The two new mobile apps Quik and Splice will help users to manage, edit, and share all of the content from GoPro cameras and mobile devices. In February, GoPro had acquired two mobile video editing apps, Replay... Fast changing fashion trends have been hitting Aeropostale badly for the last several quarters, and at last it opted for Chapter 11 bankruptcy filing on Wednesday. Google will collaborate with Fiat Chrysler Automobiles N.V. to integrate Google's self-driving technology into the 2017 Chrysler Pacifica Hybrid minivans. The collaboration will expand Google's existing self-driving test program and also marks the first time that Google will be working directly with an automaker to integrate its self-driving system.
comments powered by Disqus
Follow RTT