logo
Share SHARE
FONT-SIZE Plus   Neg

Oncolytics Meets Primary Endpoint For First Stage Of Phase 2 Lung Cancer Trial

Oncolytics Biotech Inc. (ONC.TO, ONCY) reported preliminary results from its U.S. Phase 2 trial in patients with squamous cell carcinoma of the lung or SCCLC using intravenous administration of REOLYSIN in combination with carboplatin and paclitaxel. The Principal Investigator is Alain Mita of Cedars-Sinai Medical Centre in Los Angeles, CA.

The study's primary objective is to assess the antitumor effect of the treatment regimen in the study population in terms of objective response rates, while the secondary objectives are to assess progression-free survival and overall survival for the treatment regimen in the study population; to determine the proportion of patients receiving the above treatment who are alive and free of disease progression at six months; and to assess the safety and tolerability of the treatment regimen in the study population.

The study is a two stage design, wherein up to 19 evaluable patients with SCCLC were to be treated in the first stage. If four or more patients demonstrated a partial response or better, the study would then proceed to the second stage, with up to 55 patients being treated in the entire study. This endpoint was met after 15 evaluable patients were enrolled. According to the company, five of 15 patients showed partial response, four confirmed, one unconfirmed, and an additional eight patients had stable disease, for 87% disease control rate.

The company said it is proceeding with the second stage of the study.

by RTT Staff Writer

For comments and feedback: editorial@rttnews.com

Business News

Quick Facts

Editors Pick
GOP strategist Karl Rove has criticized U.S. President-elect Donald Trump's comments on aircraft maker Boeing Co.'s contract for a new Air Force One plane, saying they were inaccurate and de-stabled the stock of a major company. Air Force One is the official air plane for the U.S. President. Elon Musk's space transport company SpaceX has lost a satellite launch order from one of its customers due to the delay in its rocket launch schedule after one of its rockets exploded in September. Free meals in coach might soon make a comeback on Delta Air Lines Inc. The Atlanta-based airline said it is testing complimentary meals in the main cabin on transcontinental flights between JFK International Airport in New York and Los Angeles International Airport or San Francisco International Airport.
comments powered by Disqus
Follow RTT