FONT-SIZE Plus   Neg

Merck, GE Healthcare Collaborate For BACE Inhibitor Development Program

Merck (MRK), known as MSD outside the U.S. and Canada, and GE Healthcare, an unit of General Electric Co. (GE), announced a study collaboration, license and supply agreement for use of [18F]Flutemetamol, an investigational positron emission tomography or PET imaging agent, to support Merck's development of MK-8931, a novel oral beta amyloid precursor protein site cleaving enzyme or BACE inhibitor and Merck's lead investigational candidate for Alzheimer's disease.

According to the agreement, GE Healthcare would supply [18F]Flutemetamol to help select patients for trials and assess this investigational agent as a companion diagnostic tool. A joint Merck and GE Healthcare Imaging Advisory Committee would oversee the planned imaging studies.

"In clinical trials, [18F]Flutemetamol demonstrated consistent performance in the visual detection of beta amyloid in the brain when compared with histopathology data," according to Jonathan Allis, general manager, PET, GE Healthcare Medical Diagnostics.

by RTT Staff Writer

For comments and feedback: editorial@rttnews.com

Business News

Editors Pick
Swiss drug giant Novartis AG reported Tuesday higher net profit in its third quarter, while sales were weak due to generic competition and pricing. Core earnings per share topped analysts' estimates, but sales missed their view. For fiscal 2016, the company continues to expect Core operating income to be broadly in line or decline low-single digit, and net sales to be broadly in line.. Social media site Twitter Inc., which is facing an uncertain future, is planning to cut around 8 percent of its total workforce, Bloomberg reported Monday citing people familiar with the matter. The company, which is trying cost control amid slowing sales growth, may announce the job cut of about 300 people as soon as this week. Visa Inc. (V) on Monday reported an increase in profit for the fourth quarter, as revenues jumped driven largely by increase in customer spending and inclusion of Europe business. Earnings and revenues trumped Wall Street expectations. Foster City, California-based Visa's fourth-quarter profit rose...
comments powered by Disqus
Follow RTT