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Addex To Get $330 Mln Potential Milestones In Licensing Deal With Indivior

Switzerland-based Addex Therapeutics announced Wednesday the signing of a licensing and collaboration agreement with Indivior PLC (INDV.L) for global development and commercialization of ADX71441 for the treatment of addiction.

Under the terms of the agreement, Addex will receive $5 million upfront, $4 million of committed research funding over the next two years, $330 million of potential development, regulatory and commercialization milestones and tiered royalties up to double-digit.

Addex retains the right to select compounds from the research collaboration for certain indications outside addiction, including Charcot-Marie-Tooth type 1a neuropathy or CMT1A.

ADX71441 is a potent, selective positive allosteric modulator or PAM that potentiates GABA responses at the GABAB receptor. In addition, Indivior will fund a research program at Addex to discover additional GABAB PAM compounds.

Tim Dyer, CEO at Addex, said, "This agreement is part of our ongoing strategy to secure resources to advance certain assets of our broad allosteric modulator pipeline with leading players in key markets."

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