Plus   Neg

Merck Says Phase 3 KEYTRUDA Trial Meets Primary Endpoint

Merck (MRK) Monday said its KEYTRUDA anti-PD-1 therapy for surgically resected high-risk melanoma met the primary endpoint of recurrence-free survival. The company, known as MSD outside the US, said phase 3 randomized, double-blind EORTC1325/KEYNOTE-054 trial resulted in significantly longer recurrence-free survival than placebo. The study will continue in order to evaluate other key endpoints, including overall survival.

Merck plans to present the results at an upcoming medical meeting.
In total, the study enrolled 1,019 patients who were randomly assigned to receive either KEYTRUDA at a flat dose of 200 mg intravenously on day 1 of each 21-day cycle for up to 1 year or placebo IV on day 1 of each 21-day cycle for up to 1 year.

by RTTNews Staff Writer

For comments and feedback: editorial@rttnews.com

Business News

Quick Facts

Editors Pick
Walmart Inc. has deepened its strategic partnership with Microsoft Corp. by choosing the technology giant as its preferred as well as strategic cloud provider and tap into the full range of Microsoft's cloud solutions. The five-year agreement brings together Amazon.com Inc.'s two major rivals. Walmart is Amazon's largest retail rival, while Microsoft is its biggest competitor in cloud computing. Goldman Sachs Group, Inc. on Tuesday reported a 44 percent surge in profit for the second quarter from last year, reflecting higher revenues across all segments. The company noted that revenues were the highest second-quarter revenue in nine years. Both revenue and earnings per share for the quarter beat analysts' expectations. The company's shares are down 0.4 percent in pre-market activity. Office sharing start-up WeWork said it will no longer serve meat at company events and also will not allow employee to expense meat. WeWork said it has made a commitment to be a meat-free organization. The company announced its meat-free policy in an internal memo to its global employees, saying that the move is intended to reduce the environmental impact of its business.
Follow RTT