logo
Plus   Neg
Share
Email

GTx Shares Up 26% On Enobosarm's Positive Results To Treat Urinary Incontinence

Shares of GTx Inc. (GTXI) is currently up 26% on the Nasdaq after the company Monday reported additional positive results from a phase 2 trial of its drug for postmenopausal women with stress urinary incontinence.

Memphis, Tennessee-based Gtx released additional results from a Phase 2 proof-of-concept clinical trial of 3 mg enobosarm administered orally in postmenopausal women with stress urinary incontinence, including magnetic resonance imaging results from patients' pelvic floor muscle.

The new data also suggests a positive treatment effect of enobosarm for urge incontinence suggesting a possible treatment effect for women with mixed incontinence.

Results from a pre-specified analysis of MRI data demonstrate a statistically significant increase in pelvic floor muscle thickness and urethral muscle diameter after enobosarm treatment. Treatment with enobosarm also reduced mean urge incontinence episodes by approximately 68 percent in patients who experienced urge incontinence as well as stress urge incontinence.

"Enobosarm's overall treatment effect was consistent with previously announced results, and importantly, these new results demonstrate that enobosarm may address a broader treatment need since many women suffer from symptoms of both stress and urge incontinence, also known as mixed incontinence," said Kenneth Peters, M.D., Chairman of Urology, Oakland University William Beaumont School of Medicine, and the principal investigator in the trial.

"In addition, with the MRI results, we are seeing anatomical changes supporting enobosarm's mechanism of action on pelvic floor muscle."

by RTTNews Staff Writer

For comments and feedback: editorial@rttnews.com

Business News

Editors Pick
A former Southwest Airlines employee has filed a racial discrimination lawsuit against the airline, alleging that the carrier allowed its employees to create a "whites-only" breakroom. The lawsuit was filed in the United States District Court in Houston earlier this week by Jamel Parker, a former employee of Southwest Airlines. American Airlines Inc. has joined its major rivals in raising baggage fees as the airline industry grapples with higher fuel costs and rising operating expenses. The largest U.S. airline said Thursday it is raising the price of a first and second checked bag by $5 each. The price of a first checked bag is now $30, while it is $40 for a second checked bag. The takeover battle by Comcast Corp. nd Rupert Murdoch's 21st Century Fox Inc. for British broadcaster Sky plc will be settled through an auction. The UK Takeover Panel said Thursday that an auction procedure is expected to commence on the evening of Friday, September 21, 2018 and end on the evening of September 22, 2018. The winner of the auction will be announced on Saturday.
Follow RTT