Before The Bell

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Express Scripts Holding (ESRX) announced after the bell Monday that its Executive Vice President and Chief Financial Officer Cathy Smith has resigned in order to pursue other interests. The company also reaffirmed its full year 2014 adjusted EPS forecast of $4.86 to $4.90. The consensus estimate...

Cyclacel Pharmaceuticals Inc. (CYCC) announced Tuesday morning that the independent Data and Safety Monitoring Board of its Phase 3 SEAMLESS study of oral sapacitabine capsules, in acute myeloid leukemia, determined that it would be unlikely for the study to reach statistically significant improvement...

Navistar International Corp. (NAV) reported a fourth quarter loss of $0.88 per share Tuesday morning, compared to the loss of $1.91 per share last year. Analysts expected a profit of $0.15 per share. Navistar International gapped open lower Tuesday and declined during the first hour of trade. The...

Novogen Ltd. (NVGN) confirmed Tuesday morning that its TRXE-009 drug has proven to be highly active against melanoma in pre-clinical studies. Novogen gapped open dramatically higher Tuesday and climbed steadily throughout the first half of the session. The stock finished with a gain of 3.67 at $5.38...

Boeing Co. (BA) announced after the close Monday that its Board of Directors has increased the company's quarterly dividend by 25 percent to 91 cents a share and raised the share buyback authorization to $12 billion. Boeing gapped open sharply higher Tuesday morning, but was range-bound throughout...

Talisman Energy Inc. (TLM) announced Tuesday morning that it agreed to be acquired by Repsol S.A. for US$8.00 per share in cash. Talisman Energy gapped open dramatically higher Tuesday, but moved in a narrow range throughout the session. The stock closed up by 2.46 at $7.58 on the highest volume...

CVS Health Corp. (CVS) announced Tuesday morning that it expects to report full year 2015 adjusted EPS of $5.05 to $5.19. The consensus estimate is for EPS of $5.11. CVS Health's board of directors also approved a 27 percent increase in the company's quarterly cash dividend to $0.35 per share. The...

Salix Pharmaceuticals Ltd. (SLXP) withdrew its previously-issued financial guidance for the fourth quarter as well as fiscal 2014 Tuesday morning, due to its decision to accelerate the reduction of wholesaler inventory levels and sell minimal amounts of Xifaxan 550, Apriso and Uceris during the fourth...

Sorrento Therapeutics Inc. (SRNE) announced Monday morning that it will establish a global strategic collaboration with NantWorks to jointly develop next generation immunotherapies for the treatment of cancer and auto-immune diseases. Dr. Patrick Soon-Shiong, the founder of NantWorks, will also acquire...

McDonald's Corp. (MCD) traded to the downside for the majority of Monday's session and closed lower by 2.16 at $88.46 on above average volume. McDonald's has been losing ground since it reported weak November sales one-week ago. The stock sank beneath support Monday and closed at a new low for the year.

Sophiris Bio Inc. (SPHS) announced Monday morning that the Independent Data Monitoring Committee for the ongoing Phase 3 trial of PRX302 reported that a predefined efficacy threshold following treatment was not achieved. PRX302 is a treatment for lower urinary tract symptoms of benign prostatic hyperplasia. Sophiris...

OPKO Health Inc. (OPK) and Pfizer Inc. (PFE) announced Monday morning that they have entered into a worldwide agreement for the development and commercialization of OPKO's long-acting hGH-CTP. Pfizer will receive the exclusive license to commercialize hGH-CTP worldwide and OPKO will receive an upfront...

Riverbed Technology Inc. (RVBD) announced Monday morning that it agreed to be acquired by Thoma Bravo LLC and Ontario Teachers' Pension Plan for about $3.6 billion. Riverbed Technology gapped open sharply higher Monday, but traded in a range for the majority of the session. Shares finished with a...

Barclays upgraded its rating on shares of Cirrus Logic Inc. (CRUS) Monday morning to "Overweight" from "Underweight." Barclays also increased its price target on the stock to $28 from $18 per share. Cirrus Logic gapped up sharply Monday and climbed throughout the first hour of trade. The stock was...

MicroFinancial Inc. (MFI) announced Monday morning that it agreed to be acquired for $10.20 per share in cash by funds managed by affiliates of Fortress Investment Group LLC. MicroFinancial gapped open dramatically higher Monday and spiked to the upside in early trade, before settling into a narrow...