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Celldex Therapeutics, Inc. (CLDX) announced the initiation of an open-label, Phase 1/2 safety and tolerability study examining the investigational combination of varlilumab and sunitinib or SUTENT in patients with metastatic clear cell renal cell carcinoma or CC-RCC. Varlilumab is Celldex's fully...

Gilead Sciences, Inc. (GILD) announced that its Marketing Authorization Application or MAA for two doses of an investigational fixed-dose combination of emtricitabine and tenofovir alafenamide or F/TAF has been fully validated and is now under evaluation by the European Medicines Agency or EMA. The...

Discount retailer Dollar General Corp. (DG) Thursday said that effective June 3, its board of directors has named Todd Vasos, chief operating officer, as the chief executive officer and has elected him to the board. Vasos will succeed Rick Dreiling, chairman and CEO, who had previously announced...

AMSC (AMSC) reported that its net loss for the fourth quarter of fiscal 2014 narrowed to $3.4 million, or $0.36 per share, from $22.7 million, or $3.30 per share, for the same period of fiscal 2013. The Company's non-GAAP net loss for the fourth quarter of fiscal 2014 was $6.4 million, or $0.69 per...

Teck Resources Limited (TCK_A.TO, TCK) said it would implement temporary shutdowns in the third quarter at its six Canadian steelmaking coal operations to align production and inventories with changing coal market conditions. Each of Teck's steelmaking coal operations will be temporarily shut down...

Bayer HealthCare, a subgroup of Bayer AG (BAYZF.PK, BAYRY.PK, BYR.L) and its development partner Janssen Pharmaceuticals, Inc. announced the initiation of the CALLISTO Clinical Research Programme to explore the potential benefits of the oral Factor Xa inhibitor Xarelto (rivaroxaban) for the prevention...

Merck & Co. Inc. (MRK) and NanoString Technologies Inc. (NSTG) announced a clinical research collaboration to develop an assay that will optimize immune-related gene expression signatures and evaluate the potential to predict benefit from Merck's anti-PD-1 therapy, KEYTRUDA or pembrolizumab, in multiple...

Agilent Technologies Inc. (A) announced its board has approved a new share repurchase program, which authorizes the purchase of up to $1.14 billion of the company's common stock through and including Nov. 1, 2018. The new repurchase program replaces Agilent's existing stock repurchase program. The...

Cardinal Health, Inc. (CAH) announced that its March 1, 2015 binding offer to acquire Johnson & Johnson's (JNJ) Cordis business for $1.94 billion in cash was formally accepted. The company noted that the offer was accepted after consultations with relevant works councils and trade unions. The transaction...

AMAG Pharmaceuticals, Inc. (AMAG) announced that it has received a complete response letter from the U.S. Food and Drug Administration or FDA regarding its manufacturing supplement seeking approval for a single-dose vial of Makena. A complete response letter is a communication from the FDA that informs...

Alliance One International, Inc. (AOI) announced a 1-for-10 reverse stock split of the company's common stock. The stock split will reduce the number of outstanding shares of Alliance One common stock, not including shares held by a subsidiary which will also be reduced, from 88.6 million to 8.86 million....

SandRidge Energy Inc. (SD) announced the commencement of a private offering of $1 billion in aggregate principal amount of senior secured notes due 2020. The issuance of the Notes will be conditioned on, among other things, the effectiveness of a fully-committed revised $500 million borrowing base...

Specialty retail apparel chain Express, Inc. (EXPR) Thursday announced a surge in first quarter net income to $13.062 million from $5.083 million in the prior year. Earnings per share more than doubled to $0.15 from $0.06. The company noted that merchandise margin expanded by 200 basis points and that...

Fred's Inc. (FRED) reported that its net loss for the first quarter ended May 2, 2015 was $29 thousand or break even per share, compared to net income of $6.1 million or $0.17 per share for the year-earlier quarter ended May 3, 2014. Analysts polled by Thomson Reuters expected the company to report a...

Abercrombie & Fitch Co. (ANF) reported a first-quarter net loss of $63.2 million or $0.91 per share, compared to a loss of $23.7 million or $0.32 per share, prior year. Excluding certain charges, the company reported an adjusted non-GAAP net loss of $37.2 million or $0.53 per share, for the first quarter....

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