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Old Mutual plc (ODMTY.PK) announced that the First Scheme became effective on 22 June 2018 in accordance with its terms. As part of the First Scheme, the demerger reduction of Capital and the Quilter demerger have now taken effect and it is expected that the Second Scheme Court Hearing will take place...

Dutch banking firm ING Group NV (ING) announced Monday that it has filed supplements to the Registration Documents for the debt issuance programmes of ING Groep N.V. and ING Bank N.V. The updates concern a change in the wording in the section 'General information - Litigation', reflecting an update...

Evotec AG (EVTCY.PK, EVOTF.PK) announced Monday that its strategic alliance with French drug giant Sanofi SA (SNYNF, SNY) in the field of diabetes has reached its second beta cell therapy milestone, resulting in a payment of 3 million euros to Evotec. This milestone was triggered after Evotec met...

Genentech, a member of the Roche Group (RHHBY), announced that the Phase III IMpower133 study met its co-primary endpoints of overall survival or OS and progression-free survival or PFS at its first interim analysis. The study demonstrated that initial (first-line) treatment with the combination of...

Boehringer Ingelheim and Eli Lilly and Company (LLY) announced findings from two new analyses of the EMPA-REG OUTCOME trial. The results included a post-hoc analysis demonstrating consistent effects for Jardiance versus placebo on renal outcomes in patients with established cardiovascular disease and...

Eli Lilly and Company (LLY) announced its ultra rapid lispro (URLi) led to improved and sustained blood sugar control after meals in people with type 1 and type 2 diabetes, according to results from three phase 1b studies evaluating URLi compared to Humalog. Across all three studies, URLi was absorbed...

Novo Nordisk Canada Inc. reported that a large real-world evidence study which included more than 4,000 adults with type 2 diabetes who were starting basal insulin for the first time, comparing the effectiveness of Tresiba (insulin degludec injection) versus Toujeo (insulin glargine U300) showed that...

MannKind Corp. (MNKD) announced that new data from the STAT study demonstrated that Afrezza provided improved time-in-range on continuous Glucose Monitoring compared to insulin aspart. The STAT study involved 60 patients with Type 1 diabetes and is the first randomized, controlled study to use continuous...

Merck (MRK) announced new data from the Comparative Trials with Sitagliptin (CompoSIT) clinical trials with JANUVIA (sitagliptin). The company said, in the CompoSIT-I study, initiation of insulin therapy while continuing treatment with JANUVIA resulted in greater blood glucose reductions and more patients...

Amgen (AMGN) announced new data that show Repatha (evolocumab) significantly reduced low-density lipoprotein cholesterol (LDL-C) and non-high density lipoprotein cholesterol (non-HDL-C) in patients with Type 2 diabetes and hypercholesterolemia or mixed dyslipidemia. The safety profile in the BANTING...

Eli Lilly and Company (LLY) reported that two investigational doses of the companys's dulaglutide (4.5 mg and 3.0 mg), as well as Trulicity (dulaglutide) 1.5 mg, provided significantly better blood sugar control with weight benefits compared to placebo in adults with type 2 diabetes. The safety and...

Array BioPharma Inc. (ARRY) announced updated safety and efficacy results, including overall survival, from the safety lead-in of the Phase 3 BEACON CRC trial evaluating the triplet combination of encorafenib, a BRAF inhibitor, binimetinib, a MEK inhibitor and cetuximab, an anti-EGFR antibody, in patients...

State Street Corp. (STT) announced it will provide more details about the proposed capital distributions after CCAR results are released by the Federal Reserve next week. State Street stated that, given the current year's more severe stress scenario and the nature of the company's business model...

Linde plc announced that the proposed business combination between Praxair, Inc. (PX) and Linde AG received unconditional antitrust clearance in Mexico, satisfying a closing condition. The completion of the business combination remains subject to timely approval by requisite governmental regulators and...

United Parcel Service (UPS) and the International Brotherhood of Teamsters have reached Handshake Agreement For New National Master Agreement. The five-year agreement, which is subject to ratification, covers Teamsters-represented UPS employees in small package roles. Negotiations continue on a number...

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