FONT-SIZE Plus   Neg
Share SHARE
mail  E-MAIL

Peregrine Begins Phase II Trial Of Bavituximab In Chronic Hepatitis C

RELATED NEWS
Trade PPHM now with 
1/10/2011 12:07 PM ET

Peregrine Pharmaceuticals Inc. (PPHM: Quote) said it has initiated a mid-stage clinical trial in patients with previously untreated genotype-1 hepatitis C virus (HCV) infection.

The company said the trial will determine the early virologic response (EVR) rate of patients after 12 weeks of therapy with Peregrine's bavituximab, a phosphatidylserine (PS)-targeting monoclonal antibody with immune-modulating potential, in combination with the antiviral drug ribavirin versus standard of care, pegylated interferon alpha 2a and ribavirin.

The primary endpoint of the study is the proportion of patients achieving early virologic response (EVR), an early predictor of which patients are likely to clear virus with continued treatment. Secondary endpoints include safety, tolerability and HCV viral kinetics.

Peregrine expects to complete enrollment shortly in an ongoing Phase Ib HCV trial and report data by mid-year.

Click here to receive FREE breaking news email alerts for Peregrine Pharmaceuticals Inc and others in your portfolio

by RTT Staff Writer

For comments and feedback: editorial@rttnews.com

comments powered by Disqus