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Abbott Labs Announces CE Marking For Architect Galectin-3 Assay - Quick Facts

Abbott Laboratories (ABT) announced CE Marking (Conformite Europeenne) for the Architect Galectin-3 assay, a test to aid doctors in assessing the prognosis of patients diagnosed with chronic heart failure or HF. The test was developed in partnership with BG Medicine Inc., (BGMD) to run on Abbott's Architect immunochemistry platform.

"Galectin-3 reflects the pathophysiology of heart failure and is one of the most powerful prognostic indicators in heart failure. It helps clinicians identify which patients are at high risk for worsening heart failure early in the course of their disease," said Rudolf de Boer, Associate Professor in Cardiology at the University Medical Centre Groningen, the Netherlands.

Heart failure, or the inability of the heart to circulate blood effectively, is associated with poor patient outcomes, a lower quality of life, and recurrent and costly health services. While the progress of HF is different for each patient, several studies demonstrate that HF patients with higher levels of a protein called galectin-3 present are more likely to have worse outcomes, including re-hospitalization and death, the company said.

The Architect Galectin-3 assay is a chemiluminescent microparticle immunoassay for the quantitative determination of galectin-3 in human serum and EDTA plasma on the Architect i System. The Architect Galectin-3 assay may be used in conjunction with clinical evaluation as an aid in assessing the prognosis of patients diagnosed with chronic heart failure.

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