Plus   Neg

AstraZeneca & Merck & Co.: SOLO-3 Trial Of Lynparza Demonstrates Positive Result

AstraZeneca (AZN.L,AZN) and Merck & Co., Inc announced positive results from the open-label Phase III SOLO-3 trial of Lynparza (olaparib) tablets in 266 patients with relapsed ovarian cancer after two or more lines of treatment. The trial was conducted as a post-approval commitment in agreement with the FDA. AstraZeneca and Merck & Co. now plan to discuss the results with the FDA.

Separately, AstraZeneca announced that the phase III OLYMPUS and ROCKIES trials for roxadustat each met their primary efficacy endpoints for the treatment of patients with anaemia in chronic kidney disease that are either non-dialysis-dependent or dialysis-dependent, respectively. Data from the phase III OLYMPUS and ROCKIES trials, together with the efficacy and pooled safety data from the global Phase III programme, will be part of the regulatory submission package in the US and other major countries.

Roxadustat is a potential first-in-class new medicine to treat anaemia in chronic kidney disease being jointly developed and commercialised by AstraZeneca and FibroGen, Inc.

For comments and feedback contact: editorial@rttnews.com

Business News

Quick Facts

Editors Pick
Viacom Inc. and AT&T Inc. said Monday they have reached a new carriage deal, averting a programming blackout that would have left AT&T's more than 24 million pay-TV customers without Viacom channels such as MTV, Comedy Central, Paramount and Nickelodeon. The renewed agreement will keep these Viacom channels on AT&T's DirectTV and U-verse pay TV services. Tribe, a blockchain accelerator backed by Singapore government, announced its partnership with BMW Group Asia, Intel and Nielsen. Tribe Accelerator said the three companies will share their knowledge and subject expertise in their respective fields with Tribe's startups. The companies will help build an inclusive ecosystem "ready for industry 4.0." MillerCoors LLC has filed a lawsuit against Anheuser-Busch Companies LLC, part of Anheuser-Busch InBev, alleging that Anheuser-Busch's ad campaigns associating MillerCoors' products, Miller Lite and Coor Light, with corn syrup is "false and misleading." During the Super Bowl, ABInBev ran an advertising campaign that mocked Miller Lite and Coors Light use corn syrup in brewing.
Follow RTT