logo
Plus   Neg
Share
Email

Stock Alert: Arrowhead Jumps 25% On Positive Results For Rare Genetic Liver Disease Treatment

Shares of Arrowhead Pharmaceuticals Inc. (ARWR) are currently gaining over 25% on Wednesday morning after the company reported positive interim results from a mid-stage trial of treatment for rare genetic liver disease.

ARWR is currently trading at $42.29, up $8.49 or 25.12%, on the Nasdaq.

Arrowhead announced positive interim 24-week liver biopsy results in four subjects from AROAAT2002.

AROAAT2002 is a phase 2 study of ARO-AAT, the company's second generation investigational RNA interference therapeutic being developed as a treatment for the rare genetic liver disease associated with alpha-1 antitrypsin deficiency.

The company said, "the results show clear evidence of a meaningful pharmacodynamic effect by ARO-AAT, leading to improvements in relevant biomarkers, including substantial reductions in intra-hepatic mutant AAT protein, both Z-AAT monomer and Z-AAT polymer; improvements in liver stiffness based on FibroScan; and, a decrease in alanine aminotransferase and gamma-glutamyl transferase, both serum biomarkers of liver injury."

For comments and feedback contact: editorial@rttnews.com

Business News

Editors Pick
Hongkong Sun Rise Trading Ltd. has recalled about 151,400 units of Kobalt Cordless Electric chainsaws and about 106,520 units of Kobalt Cordless Electric pole saws for possible laceration hazard, according to two separate statements issued by the U.S. Consumer Product Safety Commission. These include 1,400 chainsaws and 120 pole saws sold in Canada. Branded food company Hormel Foods Corp. (HRL) announced Friday that its Hormel Black Label Breakfast Food Truck will hit the road with free sample event of the popular brand's new Hormel Black Label Oven-Baked Egg Bites. The samples come in three variants - with Bacon, with Chorizo and with Bacon and... United Airlines has rolled out an interactive online "Map Search" feature for its customers in collaboration with search giant Google. The new feature is powered by Google Flight Search Enterprise Technology. United is claimed to be the first airline in the U.S. to add this feature. The new feature, available on United.com, allows customers to easily search, compare and purchase flight tickets.
RELATED NEWS
Follow RTT