logo
Plus   Neg
Share
Email

Bayer : Finerenone Drug Reduces Risk Of Cardiovascular Outcomes In CKD And Type 2 Diabetes

Bayer AG's (BAYZF.PK,BAYRY.PK,BYR.L) investigational drug finerenone reduced the risk of cardiovascular outcomes in patients with chronic kidney disease or CKD and type 2 diabetes, with or without history of cardiovascular disease, as per a pre-specified exploratory subgroup analysis of the FIDELIO-DKD Phase III study.

The FIDELIO-DKD data showed finerenone significantly reduced the risk of the key secondary endpoint, a composite of time to cardiovascular death, non-fatal myocardial infarction, non-fatal stroke or hospitalization for heart failure compared to placebo by 14 percent over a median duration of follow-up of 2.6 years.

Of the 2,605 patients with a history of cardiovascular disease, the composite cardiovascular outcome occurred in 17.7 percent of patients in the finerenone group and 20.2 percent of patients in the placebo group.

For 3,069 patients without a history of cardiovascular disease, the composite cardiovascular outcome occurred in 8.9 percent of patients in the finerenone group and in 10.2 percent of patients in the placebo group.

FIGARO-DKD, the cardiovascular outcomes study with finerenone, is due to complete in mid-2021.

The Phase III program with finerenone in chronic kidney disease and type 2 diabetes enrolled more than 13,000 patients across a broad range of disease severity including those with early kidney damage and more advanced stages of kidney disease.

For comments and feedback contact: editorial@rttnews.com

Business News

Editors Pick
CVS Health has started administering second doses of COVID-19 vaccine at skilled nursing facilities, which will be completed within four weeks. The company said its long-term care vaccination effort remains on track. The healthcare company has administered the first round of vaccine doses to nearly 8,000 skilled nursing facilities across the country. Goldman Sachs Group Inc. cut Chairman and Chief Executive Officer David Solomon's fiscal 2020 pay by $10 million as a penalty for the bank's role in 1Malaysia Development Berhad or 1MDB bribery scandal. In a filing with the U.S. Securities and Exchange Commission, the bank said it has also cut payments of President and Chief Operating Officer John Waldron, and Chief Financial Officer Stephen Scher Facebook has rolled out the Facebook News feature for users across the United Kingdom, the only destination outside the United States to get the feature. Facebook News comes as a tab in the Android or iOS version of the Facebook app that will feature news from hundreds of leading national, local and lifestyle outlets.
Follow RTT