Plus   Neg

Genentech : Ocrevus Data Reinforce Benefit On Slowing Disease Progression In Multiple Sclerosis

Genentech, a member of the Roche Group (RHHBY), said new analyses showed that early treatment with Ocrevus or ocrelizumab may significantly control disease progression in both relapsing-remitting multiple sclerosis and in primary progressive multiple sclerosis. Controlling progression can enable people with multiple sclerosis to maintain mobility and limit their disability.

In addition, data show that more people with multiple sclerosis are staying on Ocrevus, the only twice-yearly treatment for multiple sclerosis, compared with other therapies, which may translate to improved outcomes, the company said in a statement.

Ocrevus treatment provided consistent benefit over one year in patients who were recently diagnosed with relapsing-remitting multiple sclerosis or RRMS and had not received prior disease modifying treatment (DMT) in an interim analysis of open-label Phase IIIb study ENSEMBLE.

After 48 weeks, 85% of Ocrevus-treated early-stage relapsing-remitting multiple sclerosis (RRMS) patients achieved no evidence of disease activity.

Ocrevus treatment significantly slowed loss of brain tissue within T2 MRI lesions in primary progressive multiple sclerosis in post-hoc analysis of Phase III ORATORIO study.

Ocrevus-treated patients showed highest adherence and persistence rates compared with other disease-modifying therapies in two-year U.S. claims analysis.

Ocrevus is approved in 95 countries across North America, South America, the Middle East, Eastern Europe, as well as in Australia, Switzerland, the United Kingdom and the EU.

For comments and feedback contact: editorial@rttnews.com

Business News

Editors Pick
Performance Food Group Co. announced Tuesday its agreement to acquire Core-Mark Holding Co., Inc., a wholesale distributor to the convenience retail industry, in around $2.5 billion stock and cash transaction, including net debt. In pre-markey activity on Nasdaq, Core-Mark shares were gaining around 9 percent to trade at $45.86. Retail giant Walmart Inc. reported Tuesday a profit for the first quarter of fiscal 2022 that declined 31.6 percent from last year, hurt by net losses on equity investments, However, adjusted earnings per share and quarterly revenues topped analysts' expectations. The retailer also raised its guidance for the second quarter and for the full-year 2022. European Medicines Agency or EMA announced that Comirnaty, the COVID-19 vaccine developed by Pfizer and BioNTech, can have more flexible storage conditions, including up to one month in a normal fridge. The proposed change in the approved storage conditions, recommended by EMA's human medicines committee or CHMP, will help in easy handling of the vaccine in vaccination centres across the EU.
Follow RTT