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Johnson & Johnson: HIV Vaccine Candidate Fails To Provide Protection; To Discontinue Imbokodo Study

Johnson & Johnson (JNJ) said results from the primary analysis of a phase 2b vaccine clinical trial showed the investigational HIV vaccine regimen did not provide sufficient protection against the infection. This proof-of-concept efficacy study, also known as the Imbokodo study, began in 2017, and completed vaccinations in 2020. It included approximately 2,600 young women across five countries in sub-Saharan Africa. Johnson & Johnson said, based on the results, the Imbokodo study will not continue.

Johnson & Johnson noted that the phase 3 Mosaico study which is testing the safety and efficacy of a different composition of the HIV vaccine regimen among men who have sex with men and transgender individuals will continue.

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