logo
  

Syndax Partners With Incyte To Develop, Commercialize Axatilimab - Quick Facts

Syndax Pharmaceuticals, Inc. (SNDX) and Incyte (INCY) have entered into a worldwide collaboration and license agreement to develop and commercialize axatilimab, Syndax's anti-CSF-1R monoclonal antibody. Incyte will lead global commercial activities for axatilimab across all indications. The companies will participate in a 50:50 profit share in the U.S. Syndax will receive double-digit royalties on sales outside of the U.S.

Syndax said enrollment continues in the ongoing global pivotal phase 2 AGAVE-201 trial of axatilimab monotherapy in patients with chronic graft-versus-host disease, with topline data expected in 2023. Syndax will commence phase 2 proof of concept trial in idiopathic pulmonary fibrosis in early 2022.

Syndax will also receive an upfront payment of $117 million plus a $35 million equity investment, which will be purchased at $24.62 per share. The company will also be eligible to receive up to an additional $450 million in potential milestone payments.

For comments and feedback contact: editorial@rttnews.com

Business News

Editors Pick
The five-day holiday shopping period from Thanksgiving Day through Cyber Monday saw about 180 million Americans making in-store and online purchases, according to the National Retail Federation's Annual Thanksgiving Weekend Consumer Survey, conducted by Prosper Insights & Analytics. The shoppers spent an average of $301.27 on holiday-related purchases such as gifts, décor, apparel and toys. Biopharmaceutical company Immunome, Inc. (IMNM) announced Wednesday that it has conducted an assessment of the reported mutations in the new SARS-CoV-2 variant, Omicron (B.1.1.529). Based upon structural mapping of those mutations and activity against previous and current CDC variants of concern,... CVS Health said it has installed time delay safe technology in all 392 Illinois CVS Pharmacy locations, including those in Target stores, to help reduce organized retail crime. The installation of new safes for controlled substances are anticipated to help prevent pharmacy robberies. There is also potential for associated diversion of controlled substance medications, including opioid medications.
RELATED NEWS
Follow RTT