Addex Says Phase 2 Feasibility Study Of Dipraglurant For Blepharospasm Did Not Meet All Goals

Addex Therapeutics Ltd (ADXN) on Friday said Phase 2a feasibility study of dipraglurant in patients with blepharospasm did not meet all of its goals.

Blepharospasm is characterized by involuntary contractions of the eyelid muscles resulting in visual disturbance or functional blindness.

The primary objective of the Phase 2a feasibility study that enrolled 15 patients, was to evaluate the safety and tolerability of dipraglurant in patients with blepharospasm.

Addex said the study was inconclusive and did not meet all of its objectives.

Another Phase 2B/3 study of dipraglurant for the treatment of Parkinson's disease levodopa induced dyskinesia remains on track to report data in the first half of 2023, the company added.

Dipraglurant is a metabotropic glutamate receptor subtype 5 negative allosteric modulator, or mGlu5 NAM, the company said.

For comments and feedback contact: editorial@rttnews.com

Business News

Editors Pick
The Federal Communications Commission or FCC has granted SpaceX Services, Inc. authorization to use its Starlink satellite internet system on vehicles in motion. SpaceX, owned by Elon Musk, is allowed to operate consumer and enterprise Ku-band Earth Stations in Motion or ESIM using frequencies allocated to the fixed satellite service. The approval would help the company to expand its services to Loud Muscle Science, LLC is recalling certain Launch Sequence products in the United States and Canada citing the presence of undeclared Tadalafil, the U.S. Food and Drug Administration said. These tainted Launch Sequence Capsule products are marketed as dietary supplements for male sexual enhancement. The U.S. Food and Drug Administration announced the intended availability of around 17 million bottles equivalent of general infant formula to be imported from New Zealand and Ireland. Under the FDA's enforcement discretion to source more infant formula to the U.S., French food company Danone SA will send 555,000 cans Aptamil Gold Plus from New Zealand.
Follow RTT