logo
  

Sanofi-GSK Next-gen COVID-19 Booster Induces Strong Immune Response Against Variants Of Concern

Sanofi (SNYNF)m on Monday said data from the Phase 3 VAT02 Cohort 2 study showed that its next-generation Covid-19 booster vaccine candidate, which is being developed in partnership with GSK, induced strong immune response against variants of concern, including Omicron in previously-vaccinated adults.

In the study, Sanofi-GSK next-generation Covid-19 vaccine candidate generated 15-fold increase in antibody titers against D614 parent virus, 30-fold increase against Beta strain, and 40-fold increase against OmicronBA.1 in adults previously primed with mRNA COVID-19 vaccines, the company said.

The Sanofi-GSK next-generation booster candidate, which is modelled on the Beta variant antigen and including GSK's pandemic adjuvant, generated double the number of neutralizing antibodies against OmicronBA.1and BA.2 compared to the D614-based (original parent virus) booster, Sanofi added.

Results from another study named COVIBOOST VAT013 showed that following primary vaccination with two doses of Pfizer-BioNTech's Comirnaty vaccine, the Sanofi-GSK next-generation booster candidate generated a higher immune response than Pfizer-BioNTech's booster or the Sanofi-GSK first-generation booster.

For comments and feedback contact: editorial@rttnews.com

Business News

Editors Pick
The U.S. Centers for Disease Control and Prevention or CDC director, Rochelle Walensky, has initiated a reorganization of the public health agency noting that it failed to reliably meet expectations during the coronavirus pandemic period, reports said. The proposed changes for a reset in the agency are expected to help it respond quicker to new health threats. While reporting financial results for the second quarter on Thursday, department store chain Kohl's Corp. (KSS) slashed its adjusted earnings and sales growth guidance for the full-year 2022. For fiscal 2022, the company now projects adjusted earnings in a range of $2.80 to $3.20 per share on a net... Apple Inc. is planning to hold a launch event on September 7 to unveil its latest iPhone 14 line, Bloomberg reported citing people with knowledge of the matter. The tech major is also expected to roll out its latest version of three Apple Watch models including Series 8. The new products, which also include multiple new versions of Macs, and low and high-end iPads, are likely to reach stores...
Follow RTT