Organovo Holdings, Inc. (ONVO) reported details of 16-week, randomized, placebo-controlled, multi-center Phase 2 study of the non-steroidal, non-bile acid FXR agonist FXR314 for the treatment of metabolic function-associated steatohepatitis. The company said the study results showed statistically significant reduction in liver fat content from baseline in patients receiving FXR314 compared to placebo. FXR314 was also found to be safe and well tolerated.
Keith Murphy, Organovo's Executive Chairman. "Given these exciting findings, we believe the data are supportive of further clinical development of FXR314 in MASH."
Shares of Organovo Holdings are up 27% in pre-market trade on Monday.
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Business News
June 05, 2026 16:18 ET A busy week for economic news flow saw a slew of reports being released that reflected the trends in the U.S. labor market. In Europe, economic growth and inflation data gained attention as the European Central Bank and Bank of England head for policy session later in the month. In Asia, the monetary policy session of the Indian central bank was in focus as the country, a major oil importer, reels under the pressures of a weaker rupee and rising inflation.