Verastem Oncology (VSTM) said it has exercised early the option to license from GenFleet Therapeutics VS-7375, a potential best-in-class oral and selective KRAS G12D inhibitor. Also, the company announced preliminary clinical data from the Phase 1 study being conducted by GenFleet in China. Enrollment in the Phase 1 dose-escalation study in China is ongoing.
Dan Paterson, CEO at Verastem Oncology, said: "Our decision to exercise the option early for VS-7375 was based on the safety, pharmacokinetics and efficacy data to date in the Phase 1 study in China, which are in line with our expectations and, importantly, indicate that patients are generally achieving oral bioavailability with exposures that correlate with strong tumor regressions across KRAS G12D mutant preclinical models. We look forward to building on the work GenFleet has started in China to bring VS-7375 to the clinic in the U.S. in mid-2025."
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June 05, 2026 16:18 ET A busy week for economic news flow saw a slew of reports being released that reflected the trends in the U.S. labor market. In Europe, economic growth and inflation data gained attention as the European Central Bank and Bank of England head for policy session later in the month. In Asia, the monetary policy session of the Indian central bank was in focus as the country, a major oil importer, reels under the pressures of a weaker rupee and rising inflation.