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COVID-19: Drugs in Development

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The COVID-19 outbreak, which started in December 2019 in Wuhan City, China, was declared a "Public Health Emergency of International Concern" by the WHO on January 30, 2020. The outbreak was characterized as a pandemic on March 11, 2020.

Currently, there are no drugs to treat COVID-19, caused by the novel coronavirus SARS-CoV-2.

Listed below are companies that are in the race to find a treatment or vaccine for the novel coronavirus.

Subscribe to RTT Intelligent Investor for FREE 7-Day Trial with complete access to COVID-19 Drugs in Development Calendar.

Company Name
Drug
Current Stage
Next Milestone
Collaboration
Last Updated
Immunic, Inc
(IMUX)
IMU-838 for COVID-19.
Phase 2b study in combination with Tamiflu in adult patients with moderate-to-severe COVID-19 (IONIC)
Top-line data expected later in 2020
University Hospitals Coventry and Warwickshire NHS Trust
09/28/2020
Atreca Inc.
(BCEL)
Antibody Treatment for COVID-19
Research
Begin clinical testing in the first half of 2021
BeiGene Ltd. (BGNE) and IGM Biosciences Inc. (IGMS)
09/25/2020
Pfizer Inc.
(PFE)
BNT162 Vaccine program
BNT162 program includes 4 vaccine candidates; BNT162b2 has been advanced into phase 2/3 global trial
Regulatory review for BNT162b2 to be sought as early as October 2020
BioNTech SE
09/25/2020
PDS Biotechnology Corp
(PDSB)
PDS0204 COVID-19 vaccine
Preclinical studies
-
Farmacore, Brazilian Ministry of Science, Technology, Innovation and Communication (MCTIC).
09/25/2020
Akari Therapeutics Plc
(AKTX)
Nomacopan for COVID-19 pneumonia patients
Phase I/II study in the U.K. to determine the safety and effectiveness of multiple drugs for the treatment of COVID-19 (AGILE)
-
-
09/25/2020
Denali Therapeutics Inc.
(DNLI)
DNL758
Phase Ib study of DNL758 in hospitalized adult patients with severe COVID-19 lung disease
-
Sanofi
09/25/2020
CureVac N.V.
(CVAC)
mRNA coronavirus vaccine
Phase I study in Germany and Belgium
Initial results from phase I study expected early in the fourth quarter. Based on the results of the phase I trial, the COVID-19 vaccine candidate will advance into a phase IIb/III trial in Q4, 2020
CEPI, Bill & Melinda Gates Foundation and Defense Advanced Research Projects Agency (DARPA)
09/02/2020
Sanofi
( SNYNF, SNY)
Kevzara (Repurposed drug)
Phase 3 trial investigating intravenously administered Kevzara at a dose of 200 mg or 400 mg in severely or critically patients hospitalized with COVID-19 did not meet its primary endpoint and key secondary endpoint
-
Regeneron Pharmaceuticals, Inc. (REGN)
09/01/2020

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