Hemophilia A is a rare bleeding disorder caused by mutations in the F8 gene, leading to insufficient clotting factor VIII (FVIII) in the bloodstream. FVIII is crucial for normal blood clotting, and the severity of hemophilia is determined by its deficiency. Lower levels of FVIII increase the likelihood of bleeding, potentially resulting in significant health complications.
Hemophilia A occurs in about one in every 5,000-10,000 male births worldwide. Individuals with hemophilia A face heightened risks of spontaneous bleeding and bleeding post injuries or surgical procedures. This lifelong condition requires continuous monitoring and treatment.
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