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New Autism Drug Shows Promise In Lab Studies

By RTTNews Staff Writer   ✉  | Published:  | Google News Follow Us  | Join Us
rttnewslogo20mar2024

A report released Wednesday by the National Institutes of Mental Health and Pfizer states a new autism drug known as GRN-529 is showing promise in clinical studies. The drug was used in a recent study of mice that display symptoms similar to those in autistic humans.

According to a report from Boston.com, the drug is one of several new compounds in development meant to inhibit a cell receptor called mGluR5. That receptor is a key contributor in an animal condition called Fragile X, which is similar to autism. Mice given GRN-529 were less likely to display compulsive grooming habits and showed an increase in social behavior as compared to those who did not use the drug.

"Our findings suggest a strategy for developing a single treatment that could target multiple diagnostic symptoms," lead researcher Jacqueline Crawley explained in a statement.

"Many cases of autism are caused by mutations in genes that control an ongoing process - the formation and maturation of synapses, the connections between neurons. If defects in these connections are not hard-wired, the core symptoms of autism may be treatable with medications."

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