One of the hallmarks of Alzheimer's disease is the presence of neurofibrillary tangles inside neurons - i.e., the cells that make up the brain and the nervous system. The neurofibrillary tangles are composed of mutated Tau protein. So Tau is an attractive target for developing a new Alzheimer's therapy.
A study conducted on mice by researchers of the University of Montreal, led by Jean-François Côté, have found a link between a certain protein called AXL and metastases in HER2-positive breast cancer.