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COVID-19: Drugs in Development

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The COVID-19 outbreak, which started in December 2019 in Wuhan City, China, was declared a "Public Health Emergency of International Concern" by the WHO on January 30, 2020. The outbreak was characterized as a pandemic on March 11, 2020.

Currently, there are no drugs to treat COVID-19, caused by the novel coronavirus SARS-CoV-2.

Listed below are companies that are in the race to find a treatment or vaccine for the novel coronavirus.

Subscribe to RTT Intelligent Investor for FREE 7-Day Trial with complete access to COVID-19 Drugs in Development Calendar.

Company Name
Drug
Current Stage
Next Milestone
Collaboration
Last Updated
Merck & Co Inc.
(MRK)
Molnupiravir
On Nov.26, 2021, data from all enrolled participants of the MOVe-OUT study showed molnupiravir reduced the risk of hospitalization or death to 6.8% from 9.7% in the placebo group.
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Ridgeback Biotherapeutics
11/29/2021
Biotron Limited
(BITRF. OB)
BIT225 antiviral drug
BIT225 showed statistically and clinically significant efficacy against SARS-CoV-2 in animals, reported on Nov. 25, 2021
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11/26/2021
Oncotelic Therapeutics, Inc.
(OTLC)
OT 101 COVID-19 Therapeutic
Phase 2 study in hospitalized Covid-19 patients
--On Nov.23, 2021, positive safety and efficacy data were reported from the Phase 2 study of OT-101, dubbed C001.
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11/24/2021
Todos Medical, Ltd.
Tollovir
Phase 2 study
Enrollment in Phase 2 study of Tollovir completed on Nov.19, 2021
Data from the interim analysis is expected to be reviewed by Data Safety and Monitoring Board (DSMB) in the fourth quarter of 2021.
NLC Pharma
11/22/2021
SyneuRx International
Pentarlandir
On Nov.19, 2021, the company announced that pentarlandir has shown significant anti-viral properties with minimal observed side effects in the phase II study.
Phase 3 study is expected to start in 2022.
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11/22/2021
Moderna, Inc
(MRNA)
Moderna COVID-19 Vaccine
On October 20, 2021, received emergency use authorization from the FDA for a booster dose of Moderna COVID-19 Vaccine for people aged 18 to 64 who are at high risk of severe COVID-19 or whose exposure to COVID-19 puts them at risk for COVID-19 complications or severe illness, and for people aged 65 and older.
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11/22/2021
Emergex Vaccines Holding Limited
T-cell Covid-19 vaccine
On Nov.15, 2021, Swiss regulatory authorities gave clearance to start Phase 1 study of the T-cell Covid-19 vaccine candidate.
Study to be initiated at the start of January 2022.
-
11/16/2021
Roche Holding AG
(RHHBY)
Ronapreve
On November 11, 2021, EMA's Committee for Medicinal Products for Human Use (CHMP) recommended approval of Ronapreve for treating COVID-19 in adults and adolescents who do not require supplemental oxygen and who are at increased risk of their disease becoming severe, and for preventing COVID-19 in people aged 12 years and older weighing at least 40 Kg.
--On November 12, 2021, European Commission approved ronapreve to treat non-hospitalised COVID-19 patients and for prophylaxis of the disease.
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11/15/2021

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Editors Pick
Major covid vaccine makers said they are investigating Omicron, the new, heavily mutated coronavirus variant that was first detected in South Africa, and working to adapt their vaccines, if needed. The World Health Organization, which named the new variant omicron, said the new strain is a "variant of concern" that could pose a higher risk of reinfection compared to the previous mutations. This Black Friday and the following holiday season, retailers across the United States are urged to keep up their inventory amid expected surge in shopping as majority of Americans wait till last minute to fill their baskets, according to certain studies. A new Oracle Retail survey, which was conducted last week and presented earlier this week, showed that 66 percent of consumers were less than Eagle, Idaho -based Flagship Food Group is recalling certain TJ Farms Select brand frozen cauliflower, citing the potential to be contaminated with Listeria monocytogenes, the U.S. Food and Drug Administration said. The recall involves a limited number of cases of TJ Farms Select cauliflower that comes in 16 oz. packages with lot code 2077890089 and UPC code 75544000604-3.