Celgene Corp. (CELG) said Friday that the U.S. Food and Drug Administration has approved OTEZLA, the company's oral, selective inhibitor of phosphodiesterase 4, for the treatment of adult patients with active psoriatic arthritis.
A chronic disorder, psoriatic arthritis is characterized by pain, stiffness, swelling and tenderness of the joints, inflammation of specific ligaments and tendons, and a decrease in physical functioning.
OTEZLA is the only FDA-approved oral treatment for psoriatic arthritis.
The approval was based on safety and efficacy results from three multi-center, randomized, double-blind, placebo-controlled trials - PALACE 1, 2 and 3 - conducted in adult patients with active psoriatic arthritis who were inadequately controlled by disease-modifying anti-rheumatic drugs and/or biologics. More than 75% of patients were previously treated with DMARDs only and 22% of patients were previously treated with biologics.
OTEZLA is expected to be available in the U.S. in March.
For comments and feedback contact: editorial@rttnews.com
May 01, 2026 15:54 ET Central banks dominated the economics news flow this week with almost all major ones announcing their latest policy decisions and many boosted expectations for a rate hike in June. In other news, several countries released the preliminary data for first quarter economic growth. In the U.S., comments by Fed Chair Jerome Powell were also in focus as his term ends this month.