Sepracor, Inc. (SEPR) gapped open sharply lower on Thursday and has continued to fall in the first few minutes of trading. The slide has come on strong volume.
The stock is now trading at $14.43, down $3.48 on the session. The decline takes the stock off a multi-month high reached on Wednesday, bringing shares to their lowest level in more than a month.
Late Wednesday, Sepracor said its Phase II clinical trial to evaluate efficacy and safety of SEP-225289 for treatment of major depressive disorder did not meet the primary end-point.
The Marlborough, Massachusetts-based company said that the experimental depressive disorder drug did not meet the primary efficacy endpoint of reducing symptoms of depression following eight weeks of treatment, as assessed on the clinician-rated 17-item HAM-D scale.
The positive control in the study did achieve separation from placebo that was statistically significant on the primary endpoint.
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June 05, 2026 16:18 ET A busy week for economic news flow saw a slew of reports being released that reflected the trends in the U.S. labor market. In Europe, economic growth and inflation data gained attention as the European Central Bank and Bank of England head for policy session later in the month. In Asia, the monetary policy session of the Indian central bank was in focus as the country, a major oil importer, reels under the pressures of a weaker rupee and rising inflation.