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Will The Trials Of Bispecific Antibodies Add Shine To F-star Therapeutics?

By RTTNews Staff Writer   ✉   | Published:   | Follow Us On Google News   | Join Us
rttnewslogo20mar2024

Bispecific antibodies, which feature two different antigen-binding sites in one molecule, have promising applications in cancer immunotherapy. Only 3 bispecific antibodies have received FDA approval - Janssen Pharma's Rybrevant to treat adults with locally advanced or metastatic non-small cell lung cancer; Amgen's Blincyto for the treatment of patients with Philadelphia chromosome-negative (Ph-) relapsed or refractory B-cell precursor acute lymphoblastic leukemia (ALL); and Roche's Hemlibra for the treatment of patients with hemophilia.

F-star Therapeutics Inc. (FSTX), a clinical-stage biopharmaceutical company, is developing next generation bispecific immunotherapies to transform the lives of cancer patients. The lead drug candidate is FS118, a tetravalent bispecific antibody targeting lymphocyte-activation gene 3 (LAG-3; CD223) protein and programmed cell death ligand 1 (PD-L1; CD274).

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