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Biogen: Phase 2/3 DEVOTE Study Supports Clinical Benefits Of High-dose Regimen Of nusinersen

By RTTNews Staff Writer   ✉   | Published:   | Follow Us On Google News

Biogen (BIIB) announced that Nature Medicine published results from the Phase 2/3
DEVOTE study evaluating the high-dose regimen of nusinersen, comprised of 50 mg/5 mL loading and 28 mg/5 mL maintenance doses, in spinal muscular atrophy. The company said the results showed the safety and effectiveness of the high-dose regimen of nusinersen
across a broad range of people living with SMA, irrespective of age, prior
treatment experience, and baseline functional status.

The high-dose regimen of SPINRAZA or nusinersen is approved in the European Union and Japan. The high-dose regimen is under review with the FDA and has a PDUFA action date of April 3.

In pre-market trading on NasdaqGS, Biogen shares are up 0.53 percent to $177.69.

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