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FDA Calendar

PDUFA dates and FDA Panel Review dates are very important catalysts because they are ‘make or break events’ for biotech stocks.

The goal date set by the FDA for announcing its decision on a company’s New Drug Application/ Biologics License Application/sBLA/sNDA after reviewing the applications is known as the PDUFA date.

Usually, the stocks experience a run-up going into the scheduled FDA Approval decision/FDA Panel review events. So, having prior knowledge of the key dates goes a long way toward maximizing profit or minimizing loss while investing in the volatile biotech stocks.

Listed below are large cap, mid cap and small cap stocks with pending regulatory catalysts.

Get in-depth analysis and insight on investing in the high-stakes Biotech and Pharma sectors. Check out RTT Biotech Investor and our Biotech Home Page.

Company Name
Drug
Event
Outcome
Details
Lantheus Holdings Inc.
(LNTH)
LNTH-2501 (Ga 68 edotreotide), a PET Diagnostic Imaging Kit
03/29/2026
FDA decision on LNTH-2501 for use with PET imaging for localization of somatostatin receptor-positive (SSTR+) neuroendocrine tumors in adult and pediatric patients.
The company was notified by the FDA on Mar.19, 2026, that the decision date has been postponed to June 29, 2026-
Pfizer Inc.
(PFE)
HYMPAVZI (sBLA)
Q2 2026
FDA decision on HYMPAVZI to include the treatment of hemophilia A or B patients 6 years and older with inhibitors, and pediatric patients (ages 6 to 11) with hemophilia A or B without inhibitors
Pending-
AstraZeneca PLC
( AZN, AZN.L, ZEG.DE, AZN.ST)
Baxdrostat (NDA)
Q2 2026
FDA decision on baxdrostat for treatment of adult patients with hard-to-control hypertension
Pending -
Biogen Inc.
(BIIB)
Nusinersen (sNDA)
04/03/2026
FDA decision on high-dose regimen of nusinersen for people living with spinal muscular atrophy (SMA)
FDA approved high-dose SPINRAZA (nusinersen) regimen For treatment of Spinal Muscular Atrophy on 30th March 2026.-
Ionis Pharmaceuticals, Inc.
(IONS)
Nusinersen (sNDA)
04/03/2026
FDA decision on high-dose regimen of nusinersen for people living with spinal muscular atrophy (SMA)
pending-
Denali Therapeutics Inc.
(DNLI)
Tividenofusp alfa (BLA)
04/05/2026
FDA decision on Tividenofusp alfa for the treatment of Hunter syndrome
FDA granted accelerated approval of AVLAYAH (tividenofusp alfa-eknm) for the treatment of Hunter syndrome on 25th March 2026.-
Royalty Pharma plc
(RPRX)
Tividenofusp alfa (BLA)
04/05/2026
FDA decision on Tividenofusp alfa for the treatment of Hunter syndrome
FDA granted accelerated approval of AVLAYAH (tividenofusp alfa-eknm) for the treatment of Hunter syndrome on 25th March 2026.-
AstraZeneca PLC
( AZN, AZN.L, ZEG.DE, AZN.ST)
PADCEV (sBLA)
04/07/2026
FDA decision on PADCEV plus KEYTRUDA for patients with muscle-invasive bladder cancer who are ineligible for cisplatin-containing chemotherapy
FDA approved KEYTRUDA plus Padcev for the treatment of patients with muscle-invasive bladder cancer (MIBC) who are ineligible for cisplatin-based chemotherapy on Nov.21, 2025-
Merck & Co Inc.
(MRK)
KEYTRUDA (sBLA)
04/07/2026
FDA decision on KEYTRUDA plus Padcev for the treatment of patients with muscle-invasive bladder cancer (MIBC) who are ineligible for cisplatin-based chemotherapy.
FDA approved KEYTRUDA plus Padcev for the treatment of patients with muscle-invasive bladder cancer (MIBC) who are ineligible for cisplatin-based chemotherapy on Nov.21, 2025 -
Merck & Co Inc.
(MRK)
KEYTRUDA QLEX (sBLA)
04/07/2026
FDA decision on KEYTRUDA QLEX plus Padcev for the treatment of patients with muscle-invasive bladder cancer (MIBC) who are ineligible for cisplatin-based chemotherapy.
FDA approved KEYTRUDA QLEX plus Padcev for the treatment of patients with muscle-invasive bladder cancer (MIBC) who are ineligible for cisplatin-based chemotherapy on Nov.21, 2025 -

ALSO READ - COVID-19 Drugs In Development Calendar which lists Companies that are in Race to find a Treatment or Vaccine for the Novel Coronavirus.

Biotechnology Weekly Update - March 31, 2026

March 31, 2026 15:49 ET
In this week’s video, we’ll cover major biotech moves and breakthroughs - from Novartis and Merck’s blockbuster acquisitions to the first new Hunter syndrome therapy in two decades. We’ll also look at a promising alternative to daily insulin injections and the near-term catalyst for Q3 Bio, which has been hitting new 52-week highs.

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