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FDA Calendar

PDUFA dates and FDA Panel Review dates are very important catalysts because they are ‘make or break events’ for biotech stocks.

The goal date set by the FDA for announcing its decision on a company’s New Drug Application/ Biologics License Application/sBLA/sNDA after reviewing the applications is known as the PDUFA date.

Usually, the stocks experience a run-up going into the scheduled FDA Approval decision/FDA Panel review events. So, having prior knowledge of the key dates goes a long way toward maximizing profit or minimizing loss while investing in the volatile biotech stocks.

Listed below are large cap, mid cap and small cap stocks with pending regulatory catalysts.

Get in-depth analysis and insight on investing in the high-stakes Biotech and Pharma sectors. Check out RTT Biotech Investor and our Biotech Home Page.

Company Name
Drug
Event
Outcome
Details
Merck & Co Inc.
(MRK)
Doravirine/Islatravir (NDA)
04/28/2026
FDA decision on Doravirine/Islatravir, an oral, two-drug regimen for adults with HIV-1 infection that is virologically suppressed on antiretroviral therapy.
FDA approved Doravirine/Islatravir, under the brand name Idvynso, for the treatment of HIV-1 infection in adults on Apr.21, 2026-
Sanofi SA
( SNY, SNYNF, SAN.PA)
Tzield (sBLA)
04/29/2026
FDA decision on Tzield to expand to as young as one year old and above to delay the onset of stage 3 type 1 diabetes in patients diagnosed with stage 2 T1D
FDA approved Tzield to delay the onset of stage 3 type 1 diabetes in patients diagnosed with stage 2 T1D in children aged one year and above on Apr.22, 2026-
Axsome Therapeutics, Inc.
(AXSM)
AXS-05
04/30/2026
FDA decision on AXS-05 for the treatment of Alzheimers disease agitation
FDA approved AXS-05, under the brand name AUVELITY, for agitation associated with dementia due to Alzheimer’s disease on Apr.30, 2026-
AstraZeneca PLC
( AZN, AZN.L, ZEG.DE, AZN.ST)
Camizestrant (NDA)
04/30/2026
FDA panel to review Camizestrant in ER+/HER2- Early Breast Cancer After at Least 2 Years of Standard Adjuvant Endocrine Therapy whose tumours express ESR1 gene mutations
FDA panel voted against recommending approval of Camizestrant in combination with a CDK4/6 inhibitor for advanced HR-positive breast cancer on Apr.30, 2026-
AstraZeneca PLC
( AZN, AZN.L, ZEG.DE, AZN.ST)
Truqap (sNDA)
04/30/2026
FDA panel to review Truqap in combination with abiraterone for the treatment of adult patients with metastatic hormone-sensitive prostate cancer
FDA panel recommended Truqap in combination with abiraterone for PTEN-deficient metastatic hormone-sensitive prostate cancer on Apr.30, 2026-
argenx SE
( ARGX, ARGX.BR)
VYVGART (sBLA)
05/10/2026
FDA decision on VYVGART with generalized myasthenia gravis who test negative for AChR antibodies (seronegative).
FDA approved label expansion for VYVGART and VYVGART Hytrulo to include all serotypes of adult patients living with generalized myasthenia gravis on May 8, 2026-
Daiichi Sankyo Company Limited
( DSKYF, 4568.T)
ENHERTU (sBLA)
05/18/2026
FDA decision on ENHERTU followed by paclitaxel, trastuzumab and pertuzumab for the neoadjuvant treatment of adult patients with HER2 positive breast cancer
FDA approved ENHERTU in the neoadjuvant and adjuvant settings of patients with HER2-positive early breast cancer on May 16, 2026-
AstraZeneca PLC
( AZN, AZN.L, ZEG.DE, AZN.ST)
ENHERTU (sBLA)
05/18/2026
FDA decision on ENHERTU followed by paclitaxel, trastuzumab and pertuzumab for the neoadjuvant treatment of adult patients with HER2 positive breast cancer
FDA approved ENHERTU in the neoadjuvant and adjuvant settings of patients with HER2 positive early breast cancer on May 16, 2026-
Biogen Inc.
(BIIB)
LEQEMBI IQLIK (sBLA)
05/24/2026
FDA decision on LEQEMBI IQLIK, as a weekly starting dose, for the treatment of early Alzheimer’s Disease
FDA requests additional information during the review process of LEQEMBI IQLIK and extends decision by three months to Aug 24-
BioArctic AB
( BRCTF, BIOA-B.ST, BIOA_B.ST)
Leqembi Iqlik subcutaneous autoinjector (sBLA)
05/24/2026
FDA decision on Leqembi Iqlik Subcutaneous Autoinjector for the treatment of Alzheimer’s disease in patients with Mild Cognitive Impairment or mild dementia stage of disease
pending-

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