Eli Lilly and Company (LLY) Thursday announced positive topline results from the SUMMIT phase 3 study evaluating tirzepatide in adults with heart failure having preserved ejection fraction (HFpEF) and obesity.
HFpEF is a condition in which the heart's left pumping chamber becomes stiff and unable to fill properly. It is associated with symptoms including fatigue, shortness of breath, reduced ability to exercise and swelling of extremities.
Tirzepatide showed statistically significant improvements in both primary endpoints with a reduction in the risk of heart failure outcomes, improvements in heart failure symptoms and physical limitations, compared with placebo.
Further, The overall safety profile of tirzepatide in the SUMMIT trial was consistent with previously reported tirzepatide studies, including SURMOUNT and SURPASS.
Tirzepatide is already approved by the FDA for the treatment of Type 2 Diabetes and for chronic weight management.
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June 05, 2026 16:18 ET A busy week for economic news flow saw a slew of reports being released that reflected the trends in the U.S. labor market. In Europe, economic growth and inflation data gained attention as the European Central Bank and Bank of England head for policy session later in the month. In Asia, the monetary policy session of the Indian central bank was in focus as the country, a major oil importer, reels under the pressures of a weaker rupee and rising inflation.