Johnson & Johnson (JNJ) Monday announced positive interim data from the Phase 2 SunRISe-4 study of TAR-200 in combination with cetrelimab in patients suffering from muscle-invasive bladder cancer (MIBC).
Data from the ongoing study showed that TAR-200 plus cetrelimab achieved pathological complete response rate of 42 percent, nearly double compared to 23 percent with cetrelimab alone, in patients with MIBC who are ineligible or refuse neoadjuvant chemotherapy and scheduled for radical cystectomy.
Treatment-related adverse events occurred in 72 percent of patients treated with the combination regimen, compared with 44 percent treated with cetrelimab alone.
"With these promising results, TAR-200 plus cetrelimab as a neoadjuvant therapy before radical cystectomy could potentially alter how bladder cancer is treated," said Kiran Patel, Vice President, Clinical Development, Solid Tumors, Innovative Medicine, Johnson & Johnson.
For comments and feedback contact: editorial@rttnews.com
Business News
May 01, 2026 15:54 ET Central banks dominated the economics news flow this week with almost all major ones announcing their latest policy decisions and many boosted expectations for a rate hike in June. In other news, several countries released the preliminary data for first quarter economic growth. In the U.S., comments by Fed Chair Jerome Powell were also in focus as his term ends this month.