Soligenix, Inc. (SNGX), a late-stage biopharmaceutical company, Monday announced positive interim results from the ongoing investigator-initiated study (IIS) evaluating extended HyBryte in patients with early-stage cutaneous T-cell lymphoma (CTCL).
Nine patients have been enrolled and treated with HyBryte over a period of up to 54 weeks in the IIS. In the study, 75 percent of patients had a treatment success, which is a 50 percent or more improvement in the cumulative mCAILS (modified Composite Assessment of Index Lesion Severity) score. Further, HyBryte appeared to be safe and well tolerated in all patients.
"Following the initial Phase 3 FLASH study, which demonstrated the safety and efficacy of shorter courses of HyBryte therapy, we are pleased to see that continuing treatment for longer time periods is resulting in the anticipated improved outcomes for patients. The majority of patients show a strong treatment response by Week 18, a noticeable advantage over other therapies that may take six to 12 months to show improvement," stated Christopher J. Schaber, President and Chief Executive Officer of Soligenix.
A confirmatory Phase 3 FLASH2 replication study of HyBryte is underway.
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June 12, 2026 17:14 ET Major central bank action was the focus this week in economic news. The European Central Bank became the first major central bank to move in response to the rising inflationary pressures in the backdrop of the conflict in the Middle East. In North America, the U.S. inflation and trade data as well as Canada’s central bank decision gained attention. The Chinese trade data was the main news in Asia.