Vigil Neuroscience (VIGL) issued an update on the Phase 2 IGNITE open-label clinical trial evaluating iluzanebart for the potential treatment of adult-onset leukoencephalopathy with axonal spheroids and pigmented glia. The trial showed no beneficial effects on biomarker or clinical efficacy endpoints with treatment of iluzanebart in ALSP patients. Based upon these results, the Phase 2 long-term extension study is being discontinued.
Ivana Magovevi-Liebisch, President and CEO of Vigil, said: "While this is not the data outcome we hoped to see for our iluzanebart program and our patients, I am proud of what we have accomplished together. We believe our efforts and the data collected from the IGNITE clinical trial and ILLUMINATE natural history study have increased awareness and provided a deeper understanding of ALSP."
For More Such Health News, visit rttnews.com.
For comments and feedback contact: editorial@rttnews.com
September 04, 2026 15:08 ET The job report and foreign trade data were the main economic news from the U.S. in the first week of September. Elsewhere in North America, the Canadian central bank announced its latest policy decision. Inflation data from Eurozone was the highlight in Europe. The latest interest rate decision by the Reserve Bank of New Zealand drew attention in Asia.