Revolution Medicines, Inc. (RVMD) and Summit Therapeutics, Inc. (SMMT) have entered into a clinical collaboration in multiple solid tumor settings to evaluate the safety and efficacy of each of Revolution Medicines clinical-stage RAS(ON) inhibitors, including the multi-selective inhibitor daraxonrasib, G12D-selective inhibitor zoldonrasib and G12C-selective inhibitor elironrasib, in combination with Summit Therapeutics ivonescimab, a PD-1 / VEGF bispecific antibody.
The clinical collaboration aims to evaluate these combinations across three priority tumor types including RAS mutant non-small cell lung cancer, pancreatic ductal adenocarcinoma and colorectal cancer. Summit Therapeutics will supply ivonescimab for clinical research and Revolution Medicines will be the study sponsor. Each company will retain commercial rights to their respective compounds.
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May 22, 2026 14:46 ET Minutes of the latest Fed policy session was the highlight of the week along with survey data on the U.S. housing market. In Europe, survey data signaled the trends in the euro area private sector. Further, consumer price inflation data from the U.K. was in focus. In Asia, various economic indicators from China drew attention to the health of the economy.