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Genmab's Epcoritamab Combo Shows Strong Results In Follicular Lymphoma Trial

By RTTNews Staff Writer   ✉  | Published:  | Google News Follow Us  | Join Us

Genmab A/S (GMAB), Thursday announced positive results from its Phase 3 EPCORE FL-1 trial evaluating subcutaneous epcoritamab in combination with rituximab and lenalidomide for relapsed or refractory follicular lymphoma.

The study met both primary endpoints, with statistically significant improvements in overall response rate and progression-free survival. The combination reduced the risk of disease progression or death by 79 percent compared to R2 alone.

Data from this interim analysis will be presented at the upcoming ASH annual meeting and support global regulatory submissions. The U.S. FDA has accepted the supplemental Biologics License Application for priority review, with a decision expected by November 30, 2025. If approved, it would mark the first bispecific antibody combo approved in the U.S. for second-line treatment of R/R FL.

GMAB is currently trading at $22.70, up $1.18 or 5.51 percent on the Nasdaq.

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Business News

Global Economics Weekly Update -May 18 – May 22, 2026

May 22, 2026 14:46 ET
Minutes of the latest Fed policy session was the highlight of the week along with survey data on the U.S. housing market. In Europe, survey data signaled the trends in the euro area private sector. Further, consumer price inflation data from the U.K. was in focus. In Asia, various economic indicators from China drew attention to the health of the economy.

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