Olema Pharmaceuticals Inc. (OLMA) is gearing up to present mature clinical data from its Phase 1b/2 study of palazestrant or OP-1250 in combination with ribociclib. The data will be featured at the European Society for Medical Oncology (ESMO) Congress, scheduled to take place in Berlin, Germany, from October 17 to 21, 2025.
Palazestrant is Olema's lead investigational therapy, a novel oral estrogen receptor (ER) antagonist and selective ER degrader, being developed for the treatment of ER-positive, HER2-negative advanced or metastatic breast cancer. The combination with ribociclib, a CDK4/6 inhibitor, is designed to address resistance mechanisms that often emerge during endocrine therapy, particularly in patients with ESR1 mutations.
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May 01, 2026 15:54 ET Central banks dominated the economics news flow this week with almost all major ones announcing their latest policy decisions and many boosted expectations for a rate hike in June. In other news, several countries released the preliminary data for first quarter economic growth. In the U.S., comments by Fed Chair Jerome Powell were also in focus as his term ends this month.