Vera Therapeutics Inc. (VERA), a late clinical-stage biotechnology company developing treatments for immunological diseases, has a couple of clinical trial catalysts and regulatory milestones to watch in the coming months.
The company's lead product candidate is Atacicept, a fusion protein self-administered at home as a subcutaneous once-weekly injection, which is under regulatory review in the U.S. for the proposed treatment of adults with immunoglobulin A nephropathy (IgAN). The FDA decision is due on July 7, 2026. If approved, the company expects to launch Atacicept in mid-2026.
Atacicept is also being studied in a phase 2 trial, dubbed PIONEER, and in a phase 3 trial, dubbed ORIGIN 3.
-- PIONEER is a phase 2 basket trial evaluating Atacicept in expanded IgAN populations, and other autoimmune kidney diseases like pMN (Primary Membranous Nephropathy) and MCD/FSGS (Minimal Change Disease/Focal Segmental Glomerulosclerosis in participants ages 10 and above.
Initial results from the PIONEER trial are expected in 1H 2026.
-- ORIGIN 3 is a pivotal phase 3 study evaluating the effect of Atacicept vs placebo on proteinuria and renal function preservation in IgAN.
The company expects to report the two-year eGFR data from the ORIGIN 3 trial in 2027.
For the year ended December 31, 2025, Vera Therapeutics' net loss widened to $299.6 million, or $4.66 per share, from $152.1 million, or $2.75 per share, in 2024.
The company held $714.6 million in cash, cash equivalents, and marketable securities as of December 31, 2025.
VERA closed Wednesday's trading at $41.68, down 1.63%.
For comments and feedback contact: editorial@rttnews.com
Business News
June 05, 2026 16:18 ET A busy week for economic news flow saw a slew of reports being released that reflected the trends in the U.S. labor market. In Europe, economic growth and inflation data gained attention as the European Central Bank and Bank of England head for policy session later in the month. In Asia, the monetary policy session of the Indian central bank was in focus as the country, a major oil importer, reels under the pressures of a weaker rupee and rising inflation.