Pfizer Inc. (PFE) on Tuesday said it has reached settlement agreements with Dexcel Pharma, Hikma Pharmaceuticals, and Cipla over patent litigation related to Vyndamax, its treatment for transthyretin-mediated amyloid cardiomyopathy (ATTR-CM).
Under the agreements, the effective U.S. patent expiry for Vyndamax has been extended to June 1, 2031, subject to ongoing litigation outcomes. Pfizer had earlier expected a revenue decline beginning in 2029 due to patent expiry, but now anticipates relatively stable U.S. sales from 2028 through mid-2031.
Vyndamax remains the market leader in ATTR-CM treatment, accounting for about 75% of prescription volume. The once-daily therapy has demonstrated significant reductions in all-cause mortality and cardiovascular-related hospitalizations.
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April 24, 2026 15:15 ET Economics news flow was relatively light this week even as the conflict in the Middle East continued, raising concerns for policymakers. In the U.S., spending data, initial jobless claims and pending home sales were the highlights. Business confidence in the biggest euro area economy was in focus in Europe. Inflation data from Japan gained attention in Asia.