Genentech, a subsidiary of Roche Holding AG (ROG.VX, RHHBY.PK), Wednesday reported the acceptance by the US Food and Drug Administration, or FDA, of its new drug application, or NDA, for vismodegib as a therapy for basal cell carcinoma in adults who cannot undergo surgery. The company also reported the application receiving a Priority Review status, with an action date of March 8, 2012.
The application is based on a Phase II study dubbed ERIVANCE which showed that vismodegib, which inhibits signaling in the Hedgehog Pathway, caused tumors to shrink substantially, or cured any visible lesions in basal cell carcinoma, or BCC patients. There are current FDA-approved medicines for BCC.
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April 17, 2026 15:29 ET The ongoing conflict in the Middle East continues to raise concerns for policymakers who worry about the impact of the supply shock and high energy prices on the real economy. Producer price data and various survey results on the housing market were the main news from the U.S. this week. In Europe, industrial production data for the euro area gained attention. GDP figures out of China and the policy move by the Singapore central bank were in focus in Asia.