Plus   Neg

BioPharmX: Phase 2b Trial Of BPX-04 Meets Primary, Secondary Endpoints

BioPharmX Corp. (BPMX), a specialty pharmaceutical company focused on medical dermatology products, announced Tuesday positive results from its Phase 2b clinical trial of BPX-04 for papulopustular rosacea.

In pre-market activity, BioPharmX shares were gaining around 62 percent to trade at $1.43.

BPX-04 is a novel topical gel formulation of fully solubilized minocycline for the treatment of moderate-to-severe papulopustular rosacea.

The randomized, double-blind, vehicle-controlled Phase 2b trial enrolled 206 subjects aged 18 years and above with moderate-to-severe papulopustular rosacea. The study evaluated the safety and efficacy of once daily application of BPX-04, versus a vehicle control over a 12-week treatment period.

The company noted that BPX-04, a 1% minocycline gel, successfully met both the primary and secondary endpoints of the trial. It demonstrated a statistically significant mean change in the number of facial inflammatory lesions and a two-grade improvement to clear or almost clear on the Investigator's Global Assessment or IGA scale from baseline to week 12.

David Tierney, BioPharmX CEO, said, "Based on the efficacy and safety profile, we believe BPX-04 has the potential to be the best-in-class treatment for papulopustular rosacea."

For comments and feedback contact: editorial@rttnews.com

Business News

Editors Pick
DMM Vission is recalling five lots of Cleaner Hand Sanitizer due to potential presence of methanol (wood alcohol), the U.S. Food & Drug Administration said in a statement. The company is yet to receive any reports of adverse events involving the product. Facebook Inc. said it will ban ads that seek to delegitimize the Presidential election. The announcement is in line with the social media giant's decision to prohibit ads that make premature declarations of victory as it aims to protect the integrity of the upcoming U.S. 2020 elections. Rob Leathern, Director of Product Management, in a tweet said that these changes apply to ads across Facebook... While reporting financial results for the first quarter of fiscal 2021 on Thursday, Conagra Brands, Inc. (CAG) provided only its adjusted earnings and organic net sales growth guidance for the second quarter of fiscal 2021. The company is still not initiating annual outlook, as is usual, as the impact...
Follow RTT