Outlook Therapeutics Inc. (OTLK), which is focused on developing an ophthalmic formulation of Bevacizumab for use in retinal indications, has a clinical trial event scheduled for this quarter.
Roche's Bevacizumab, sold under the brand name Avastin among others, is a drug used to treat various forms of cancer. It is also used off-label to treat eye diseases like wet age-related macular degeneration. Since there are no approved ophthalmic formulations of Bevacizumab, clinicians wishing to treat retinal patients with Bevacizumab have to use unapproved repackaged IV Bevacizumab provided by compounding pharmacies. This approach carries risks of contamination and inconsistent potency and availability.
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