Roche (RHHBY) announced results from two clinical trials evaluating astegolimab in people with moderate to very severe chronic obstructive pulmonary disease or COPD, alongside standard maintenance therapy.
The pivotal Phase IIb ALIENTO trial met its primary endpoint, showing a statistically significant 15.4% reduction in annualized exacerbation rate (AER) at 52 weeks, with dosing every two weeks.
In contrast, the Phase III ARNASA trial did not meet its primary endpoint, recording a numerical AER reduction of 14.5% at 52 weeks, which did not reach statistical significance.
The company noted that results across secondary endpoints were generally consistent in both studies. The overall number of exacerbations was lower than anticipated. Astegolimab's safety profile aligned with previously reported data, with no new safety signals identified.
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June 05, 2026 16:18 ET A busy week for economic news flow saw a slew of reports being released that reflected the trends in the U.S. labor market. In Europe, economic growth and inflation data gained attention as the European Central Bank and Bank of England head for policy session later in the month. In Asia, the monetary policy session of the Indian central bank was in focus as the country, a major oil importer, reels under the pressures of a weaker rupee and rising inflation.