Several biotechnology and healthcare companies posted notable gains in after-hours trading on Wednesday, driven by clinical updates, financial results, and upcoming industry presentations.
ALX Oncology Holdings Inc. (ALXO) surged 10.17% to $1.30. The company recently announced positive data from a Phase 2 investigator-sponsored trial of its lead candidate, evorpacept. The therapy, combined with rituximab and lenalidomide, showed promise in patients with indolent B-cell non-Hodgkin lymphoma.
Globus Medical, Inc. (GMED) climbed 9.34% to $99.00 following the release of preliminary unaudited sales results. The company reported fourth-quarter 2025 sales of about $823.2 million, up 25.2% year-over-year. Full-year 2025 sales are expected to reach $2.936 billion, representing a 16.5% increase from the prior year. Looking ahead, Globus Medical set its 2026 revenue guidance between $3.18 billion and $3.22 billion, with projected non-GAAP earnings per share in the range of $4.30 to $4.40.
Acrivon Therapeutics, Inc. (ACRV) rose 6.44% to $3.14 after announcing plans to release clinical data updates for ACR-368 and ACR-2316. The company said it will issue a press release at 7:30 a.m. ET on January 8, 2026, followed by a conference call and webcast at 8:30 a.m. ET.
RenovoRx, Inc. (RNXT) gained 4.95% to $1.06 despite no company-specific news being reported on Wednesday.
AnaptysBio, Inc. (ANAB) advanced 1.75% to $46.00 after confirming that CEO Daniel Faga will present at the 44th Annual J.P. Morgan Healthcare Conference on Tuesday, January 13, 2026.
Omeros Corp. (OMER) added 4.47% to $14.72, also without any fresh corporate updates.
EUDA Health Holdings Limited (EUDA) increased 3.73% to $2.50 after announcing an amendment to its warrant agreement with Streeterville Capital, LLC. The Singapore-based healthcare provider operates across Singapore, Malaysia, and China, focusing on non-invasive medical services.
TherapeuticsMD, Inc. (TXMD) rose 5.34% to $2.15 in after-hours trading, with no new announcements reported.
Pyxis Oncology, Inc. (PYXS) gained 4.93% to $1.49, also without any fresh news on Wednesday.
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